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Can you take vitamin B on an empty stomach? Vitamin B12 is also better absorbed on an empty stomach because an acidic environment increases absorption. B -complex vitamins should be taken early in the day, preferably with your first meal, as they help the body produce energy from food and taking them later in the day can interfere with your sleep.
Can I take b12 at night? Although there is no difference in the way you should take a B12 supplement at night as opposed to during the day, some people have trouble sleeping when they take B12 at night. If you have trouble sleeping, you may prefer to take your B12supplement early in the day.
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